1970年1月至1972年7月,尼日利亚某医院共收治脑膜炎球菌病717例,发生一种或多种下述变态反应性并发症者53例,占7.4％。年龄较长的患者并发症发生率较高。严重菌血症者较易于发生。关节炎:47例(6.6％),平均于发病的5.7±2.7天后出现。17例(36％)发生于单个大关节,如膝或腕关节;30例(64％)累及多数关节,一般为双侧大关节,如膝、腕、肘及踝关节;小关节如掌指关节偶可累及。关节积液最常见于膝关节,肘和腕关节亦有发生。 From January 1970 to July 1972, 717 cases of meningococcal disease were treated in a hospital in Nigeria. One or more of the following allergic complications occurred in 53 cases (7.4%). Older patients have a higher complication rate. Severe bacteremia is more likely to occur. Arthritis: 47 (6.6%), with an average of 5.7 ± 2.7 days of onset. Thirty-seven (36%) occurred in a single large joint, such as the knee or wrist; 30 (64%) involved most of the joints, usually bilateral large joints such as knees, wrists, elbows and ankles; Even the joints can be involved. Joint effusion is most common in the knee, elbow and wrist also occurred.