胃食道返流是常见疾病之一,是由于食道联合部功能不全面引起胃酸、胃蛋白酶、胆盐、胰酶等进入食道。胃食道返流发生率很高,但大部分人并无症状,这种返流究竞是生理性的还是病理性的,这就需要对返流和抗返流为机理,食道粘膜的防禦机理等作全面的分析。胃食道抗返流机理腹腔的正压可通过胃食道联合部传递到胸腔的负压,下食道括约肌是防止胃内容物返入食道的主要因素,此外尚有心膈角、膈夹、食管韧带,胃褶和远端的食道旁压力的作用。下食道括约肌是胃食道联合部的一条2—5厘米宽的加压环状带,其肌纹理不同于食道和胃的肌肉层。括约肌平时是强力收 Gastroesophageal reflux is one of the common diseases, is due to incomplete esophageal joint function caused by gastric acid, pepsin, bile salts, pancreatin into the esophagus. The incidence of gastroesophageal reflux is high, but most people are asymptomatic, this study is competing physiological or pathological competition, which requires the mechanism of reflux and anti-reflux, the esophageal mucosal defense mechanism For a comprehensive analysis. Gastroesophageal Anti-reflux Mechanism The positive pressure in the abdominal cavity can be transmitted to the chest by the gastroesophageal junction negative pressure, the lower esophageal sphincter is to prevent the stomach contents back into the esophagus, the main factors, in addition there are diaphragmatic angle, diaphragm clamp, esophageal ligament, Gastric folds and distal esophageal pressure. The lower esophageal sphincter is a 2-5 cm wide, compressed annular zone of the gastroesophageal junction that has a different muscle texture than the muscular layer of the esophagus and stomach. Sphincter usually is a strong income