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目的探讨短期胰岛素泵(CSII)联合动态血糖监测(CGMS)强化治疗对新诊断的T2DM患者的中远期疗效。方法随访观察36例新诊断的T2DM患者进行为期两周胰岛素泵强化治疗后的血糖控制及不服用药物血糖达标持续时间。结果 CSII治疗3d后血糖达标率69.4%,7d血糖达标率88.9%,2周血糖达标率97.2%;缓解期超过3个月的患者共31例(86.1%),超过6个月23例(63.9%),超过12个月16例(44.4%),超过18个月10例(27.8%)。结论联合CGMS,胰岛素泵强化治疗可迅速使新诊断的T2DM患者血糖达标,使残存胰岛β细胞得到一定程度恢复。
Objective To investigate the short-term insulin pump (CSII) combined with dynamic glucose monitoring (CGMS) intensive treatment of newly diagnosed T2DM patients with long-term efficacy. Methods Thirty-six newly diagnosed T2DM patients were followed up for glycemic control after two weeks’ intensive insulin pump treatment and the duration of non-medication blood glucose compliance. Results The blood sugar compliance rate was 69.4%, the blood glucose level was 88.9% at 7 days and 97.2% at 2 weeks after CSII treatment. There were 31 patients (86.1%) over 6 months and 23 patients (63.9) over 6 months %), 16 cases (44.4%) over 12 months and 10 cases (27.8%) over 18 months. Conclusions The combined treatment of CGMS and insulin pump can rapidly up-regulate the blood glucose of newly diagnosed T2DM patients and restore the residual islet β-cells to a certain extent.