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目的探讨以苯甲酸、水杨酸、碘为主药配制灭癣酊的制备方法、质量控制和临床疗效。方法制定处方,考察初步稳定性,并用于手癣、足癣、体癣及股癣等患者,进行临床疗效观察。结果灭癣酊质量稳定,疗效显著,与达克宁霜无显著差异。结论灭癣酊是临床治疗浅部皮肤真菌病的理想制剂。
OBJECTIVE To study the preparation, quality control and clinical curative effect of annulent tincture prepared with benzoic acid, salicylic acid and iodine as the main drug. Methods To formulate prescriptions, investigate the preliminary stability, and used in patients with hand ringworm, tinea pedis, tinea corporis and tinea cruris to observe the clinical curative effect. Results Off ringworm tincture of stable quality, significant effect, no significant difference with the dacronide cream. Conclusion Annihilation tincture is an ideal preparation for clinical treatment of superficial dermatophytosis.