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1 临床资料患者,男,17岁,入院31小时前自服异烟肼约100片(10g)。服药后约20分钟出现意识障碍,全身抽搐。急送当地医院急救。治疗期间发生3次心跳骤停,每次持续时间约2分钟。CPR术后心跳恢复,机械通气维持呼吸。当时病情危急,未进行洗胃,用Vit B_6(总量约1g)解毒及止痉等对症治疗后无缓解。于2001年5月14日转入我院急诊ICU。查体:T 36.8℃,P 110次/min,BP 117/60 mmHg,无自主呼吸,机械通气。深昏迷,GCS 3分,双侧瞳孔等大等圆,约0.25cm,光反射消失。肌张力增高,双侧病理征(-)。辅助
1 clinical data patients, male, 17 years old, 31 hours before admission, self-service isoniazid about 100 (10g). About 20 minutes after taking the symptoms of disturbance, convulsions. Urgent delivery to the local hospital emergency. Three cardiac arrests occurred during the treatment, each lasting about 2 minutes. CPR heartbeat recovery, mechanical ventilation to maintain breathing. At that time critical condition, no gastric lavage, with Vit B_6 (total about 1g) detoxification and antispasmodic symptomatic treatment without remission. On May 14, 2001 transferred to our hospital emergency ICU. Examination: T 36.8 ℃, P 110 times / min, BP 117/60 mmHg, no spontaneous breathing, mechanical ventilation. Deep coma, GCS 3 points, bilateral pupils and other large round, about 0.25cm, light reflex disappears. Muscle tension increased bilateral pathology (-). Auxiliary