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中医学将旱芹(Apium graveolens)用于治疗高血压。药理实验证实3-正丁基酞内酯(BuPh)为其降压有效成分。本次研究了其降压作用机制。 BuPh(由美国Rush大学合成和提供,纯度超过97.0％)的降血压和血管舒张作用及其可能的作用机制均采用自发性高血压大鼠
Chinese medicine will use Apium graveolens for the treatment of hypertension. Pharmacological experiments confirmed that 3-n-butyl-decanolide (BuPh) was its effective antihypertensive ingredient. The mechanism of antihypertensive effect was studied in this study. The hypotensive and vasodilating effects of BuPh (synthesized and provided by Rush University, U.S., with a purity of more than 97.0%) and their possible mechanisms of action are all using spontaneously hypertensive rats.