研究肝大部切除大鼠腹腔注射小量外源内毒素后血浆内毒素含量和谷丙转氨酶（ＳＧＰＴ）活性的变化。结果：大鼠肝２／３切除并腹腔注入小量内毒素后２４ｈ，动物死亡率明显增加，血清内毒素含量和ＳＧＰＴ活性亦显著升高。相反。假手术组注入同量内毒素，对机体却无任何影响。提示：小剂量内毒素加剧了肝大部分切除大鼠所致的急性肝损伤。 To study the changes of plasma endotoxin and glutamic-pyruvic transaminase (SGPT) activity after intraperitoneal injection of a small amount of exogenous endotoxin in rats with subtotal hepatic resection. Results: After 2/3 of hepatectomy and intraperitoneal injection of a small amount of endotoxin, the mortality rate of animals was significantly increased, and the levels of endotoxin and SGPT activity were also significantly increased. in contrast. Sham group injected with the same amount of endotoxin, but no effect on the body. Tip: A small dose of endotoxin aggravates acute liver injury in most of the resected rats.