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目的：探讨常规化疗后结核瘤的手术适应证。方法：对化疗后手术切除的１２例结核瘤的肺标本进行组织细菌学检查。结果：结核瘤中坏死及液化灶周围约５０％可分离到结核菌，其中结核瘤直径＞３ｃｍ的分离率较高，且所分离到的结核菌对不同药物有不同程度的耐药。在病理组织切片中大部分可找到抗酸菌。结论：结核瘤虽经常规化疗，但病灶外层的纤维组织使血液供应障碍药物难以渗入，致化疗效果常不理想，少部分甚至产生耐药，所以手术治疗部分结核瘤病例仍属必要
Objective: To investigate the indications of tuberculoma after conventional chemotherapy. Methods: Tissue bacteriological examination was performed on lung specimens of 12 cases of tuberculous tumors resected after chemotherapy. Results: Mycobacterium tuberculosis could be isolated from tuberculoma by necrosis and about 50% around the liquefaction stove. The separation rate of tuberculoma> 3cm in diameter was high, and the isolated tubercle bacillus had different degrees of resistance to different drugs. Most of the pathological tissue sections can find acid-fast bacteria. Conclusion: Although conventional tuberculosis chemotherapy, but the outer layer of the fibrous tissue of the blood supply difficult to infiltrate the drug, resulting in chemotherapy often unsatisfactory, and even a small part of the resistance, so the surgical treatment of some cases of tuberculosis is still necessary