自Naib提出生殖道HSV-2感染与宫颈癌发生有关这一假设以来,许多学者试图在宫颈癌组织中证明HSV-2 DNA的存在。1972年Frenkel等首先报道在宫颈癌组织中发现HSV-2 DNA序列,此标本含有39％的病毒基因组,以后许多学者应用相似的方法在有限量的标本中均未证实这一观察。近年来少部分学者 Since Naib put forward the hypothesis that genital HSV-2 infection is associated with cervical cancer, many scholars have tried to prove the existence of HSV-2 DNA in cervical cancer. Frenkel et al. First reported in 1972 that HSV-2 DNA sequence was found in cervical cancer tissues. This specimen contains 39% of the viral genome. Many scholars later did not confirm this observation in a limited number of specimens by a similar method. In recent years a small number of scholars