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一、病例一49岁女性患者因喉头肿瘤(颗粒细胞瘤)而入院。为喉头肿瘤术前准备而行气管切开,并予以抗生物质头孢噻肟、CRMN及组胺H_2拮抗剂以预防感染。7天后,躯干出现皮疹,第10天开始发热,高达39℃。胸部X线,病变以右肺尤为明显,形成一周围透光区,出现宛如蝶形的浸润影。既往无心、肾疾患,超声波、心电图等亦无急性心褒迹象。血沉、CRP增快,但周围血中白细胞不增加,嗜酸性细胞6%。根据其临床经过,检查所见,首先怀疑药物性肺损害的可能,停用上述抗生物质。3天后胸部X线检查异常
First, the case A 49-year-old female patient admitted to hospital for laryngeal neoplasm (granulosa cell tumor). Tracheotomy for laryngeal tumor preoperative preparation, and to antibiotics cefotaxime, CRMN and histamine H 2 antagonist to prevent infection. After 7 days, the skin rashes on the trunk and fever on day 10, reaching 39 ° C. Chest X-ray, the lesion to the right lung is particularly evident, the formation of a translucent area around, like a butterfly-like infiltration shadow. Past no heart, kidney disease, ultrasound, ECG, etc. No acute heart praise. Erythrocyte sedimentation rate, CRP increased, but the peripheral blood leukocytes did not increase eosinophils 6%. According to its clinical experience, the inspection found that the first suspected drug-induced lung damage, disable the above anti-biomass. Thoracic X-ray examination was abnormal after 3 days