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目的研究血清γ球蛋白（γG）及胆碱酯酶与肝组织病理损害的关系．方法采用醋酸纤维薄膜法测定135例经病理证实的慢性肝炎，肝炎肝硬变及重型肝炎的血清γG；同时采用酶速率法测定他们的血清胆碱酯酶（SChE）活力结果随着肝组织纤维化程度和（或）炎症程度的加重，血清γG逐渐升高，而SChE活力则逐渐下降，差异非常显著（P＜0．01）；γG与ChE活力的相关系数为-0．612．结论血清γG的水平能准确地反映肝脏的病理损害；SChE活力能很好地反映肝脏的合成功能，肝脏的储备功能，亦能准确地反映肝脏的病理损害．
Objective To study the relationship between serum gamma globulin (γG) and cholinesterase and pathological damage of liver tissue. Methods The serum γG of 135 cases with chronic hepatitis, cirrhosis and severe hepatitis confirmed by pathology was determined by the cellulose acetate membrane method. Meanwhile, the activity of serum cholinesterase (SChE) (P <0.01). The correlation coefficient between γG and ChE activity was -0.612. The correlation coefficient between γG and ChE activity was -0.612. Conclusion The level of serum γG can accurately reflect the pathological damage of the liver. The activity of SChE can well reflect the synthesis function of the liver and the reserve function of the liver, and can also accurately reflect the pathological damage of the liver.