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目的探讨乳腺癌前哨淋巴结活检术(SLNB)在临床应用中的价值。方法应用亚甲蓝染色法对58例乳腺癌患者先行SLNB,随后行乳腺癌常规外科手术。结果58例患者中前哨淋巴结(SLN)检出率为93.1%,准确率为96.3%,假阴性率为5.71%,假阳性率为0;操作者的学习曲线、患者的年龄、原发肿瘤的部位影响SLN的检出率(P<0.05);肿瘤的大小、病理类型不影响SLN的检出率(P>0.05)。结论乳腺癌SLNB能够准确地预测乳腺癌患者腋窝淋巴结(ALN)的转移情况。
Objective To investigate the clinical value of sentinel lymph node biopsy (SLNB) in breast cancer. Methods 58 patients with breast cancer were treated with methylene blue staining before SLNB followed by conventional surgery of breast cancer. Results The detection rate of sentinel lymph node (SLN) in 58 patients was 93.1%, the accuracy rate was 96.3%, the false negative rate was 5.71% and the false positive rate was 0. The operator’s learning curve, patient’s age, primary tumor The location affected the detection rate of SLN (P <0.05). The size and pathological type of tumor did not affect the detection rate of SLN (P> 0.05). Conclusion Breast cancer SLNB can accurately predict the metastasis of axillary lymph nodes (ALN) in breast cancer patients.