单核吞噬细胞是一种抗原提呈细胞,参与免疫反应,并在免疫应答中起调节作用。为了探讨继发性免疫缺陷的机理,作者研究了单核吞噬系统功能缺陷鼠模型的体液免疫应答。实验采用C_(57)BL/6 18—20g重雄性鼠,每天用Hank′s液冲洗一次腹腔,连续12天,使单核吞噬系统功能选择性缺陷,然后将胸腺依赖及非胸腺依赖性抗原注入腹腔,研究 Mononuclear phagocytes are antigen presenting cells that are involved in the immune response and play a regulatory role in the immune response. To explore the mechanism of secondary immunodeficiency, the authors studied the humoral immune response in a murine model of functional failure of the mononuclear phagocytic system. Experiments using C57BL / 618-20g heavy male rats were washed once daily with Hank’s liquid peritoneal cavity for 12 consecutive days to make the mononuclear phagocytic system functionally selective defects, and then thymus-dependent and non-thymus-dependent antigen Into the abdominal cavity, research