胰岛素对主要胰岛素敏感组织作用的缺陷(脂肪组织、肌肉和肝脏)被认为会导致慢性、低水平炎症状态的恶化。这种关系是双向的,与触发因子和始动事件无关;任何与慢性炎症有关的过程都会削弱胰岛素作用,作为恶性循环,胰岛素抵抗又会使炎症恶化[1]。1胰岛素对脂肪组织和炎症的作用 Defects in insulin action on major insulin-sensitive tissues (adipose tissue, muscle and liver) are believed to result in worsening of chronic, low-level inflammatory conditions. This relationship is bi-directional and has nothing to do with triggering and initiating events; any process associated with chronic inflammation weakens insulin action and, as a vicious circle, insulin resistance worsens the inflammation [1]. 1 insulin on adipose tissue and inflammation