论文部分内容阅读
目的:探析围绝经期症状与血脂水平、血清性激素之间的相关性。方法:选择250例女性为研究对象,将其分为四组,分别是育龄对照组(n=60)、围绝经期组(n=60)、绝经早期组(n=65)及绝经晚期组(n=65),分别对其进行睾酮(T)、血清雌二醇(E2)、三酰甘油(TG)、卵泡刺激素(FSH)以及总胆固醇(TC)测定,调查绝经指数(KMI),比较各组的检测结果,并对其相关性进行分析。结果:相比较育龄对照组而言,围绝经期组、绝经早期组以及绝经晚期组的T、E2水平下降明显,且FSH水平升高明显,比较差异显著(P<0.05);与育龄对照组比较,绝经晚期组、绝经早期组以及围绝经期组的TG、TC水平升高明显,组间比较差异显著(P<0.05);同时,TC与KMI呈现出正比关系,则TG则与KMI呈现出反比关系。结论:睾酮和雌二醇在女性绝经后明显下降,而卵泡刺激素明显上升,并且血清雌二醇与绝经指数呈反比关系,加强围绝经期女性的血脂水平和血清性激素监测,有助于改善绝经症状,使女性生活质量提高。
Objective: To explore the relationship between perimenopausal symptoms and serum lipids, serum sex hormones. Methods: Two hundred and fifty women were selected as study subjects and divided into four groups: control group (n = 60), perimenopausal group (n = 60), early menopause group (n = 65) and postmenopausal group (n = 65). The testosterone (T), serum estradiol (E2), triglyceride (TG), follicle stimulating hormone (FSH) and total cholesterol (TC) , Comparing the test results of each group, and analyzing their correlation. Results: Compared with the control group, the levels of T and E2 in the perimenopausal group, the early menopause group and the late menopausal group decreased significantly and the level of FSH increased significantly (P <0.05). Compared with the control group Compared with the premenopausal group, the premenopausal group and the perimenopausal group TG, TC levels increased significantly (P <0.05); at the same time, TC and KMI showed a positive correlation, TG and KMI presented An inverse relationship. Conclusion: Testosterone and estradiol decreased significantly in women after menopause, while follicle-stimulating hormone increased significantly, and serum estradiol was inversely proportional to menopause index, which could improve the level of serum lipids and serum sex hormone in perimenopausal women Menopausal symptoms, improve the quality of life of women.