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本文对中国四川泸州地区汉族273名健康无关个体进行22个非CODIS STR基因座遗传多态性调查。采用自主研制的PCR复合扩增体系对血痕样本直接扩增,用3730xl遗传分析仪检测。结果在22个STR基因座共检出180个等位基因和444种基因型,其分布符合Hardy-Weinberg平衡定律(P>0.05)。所调查的四川泸州地区汉族人群22个非CODIS STR基因座具有较好识别能力。
In this paper, 22 non-CODIS STR loci genetic polymorphisms were investigated in 273 Han unrelated individuals in Luzhou, Sichuan Province, China. Using self-developed PCR multiplex amplification system for direct amplification of bloodstain samples, with 3730xl genetic analyzer. Results A total of 180 alleles and 444 genotypes were detected in 22 STR loci. The distribution was in accordance with the Hardy-Weinberg equilibrium (P> 0.05). Twenty-two non-CODIS STR loci in the Han population surveyed in Luzhou, Sichuan province were well-identified.