人麻风临床表现呈宽光谱带现象,从LL 端至 TT 另一端,这种表现似乎取决于个体对麻风杆菌细胞免疫反应的差异。这种变化的基础尚未清楚。在整个麻风光谱中,巨噬细胞功能及免疫机制起了重要的作用,因而研究多型麻风巨噬细胞溶酶体的状态和功能是有用的。溶酶体是亚细胞器,其特征为多形性,不易通过典型的大小或结构进行鉴 Clinical manifestations of human leprosy showed a broad band phenomenon, from the LL end to the other end of the TT, which appears to depend on the individual’s immune response to leprosy differences in cellular immunity. The basis for such changes is not yet clear. Macrophage function and immune mechanisms play an important role in the whole spectrum of leprosy and it is therefore useful to study the status and function of the lysosomes of multi-type leprosy macrophages. Lysosomes are subcellular organelles characterized by pleomorphism that are not easily characterized by typical size or structure