目的:评价坦索罗辛对上尿路结石患者体外冲击波碎石术(ESWL)后辅助排石的临床疗效。方法:选取2014年1月—2015年1月间收治的上尿路结石患者100例为观察对象,将其分为对照组和实验组,每组50例;两组患者均接受ESWL治疗,对照组患者同时口服肾石通冲剂,实验组患者给予口服盐酸坦索罗辛缓释胶囊治疗,比较两组患者对上尿路结石患者体外冲击波碎石术(ESWL)后辅助排石的临床疗效。结果:实验组患者治疗后收缩压为(122.06±12.43)mm Hg和舒张压为(75.26±5.43)mm Hg略低于对照组为(128.39±21.32)mm Hg和(77.36±7.45)mm Hg;实验组患者治疗后结石排除率为88.00%显著高于对照组为70.00%;实验组患者各项临床观察指标明显优于对照组(P<0.05)。结论:盐酸坦索罗辛缓释胶囊用于上尿路结石患者体外冲击波碎石术(ESWL)后辅助排石的临床疗效优于肾石通冲剂的治疗。 Objective: To evaluate the clinical efficacy of tamsulosin in the treatment of patients with upper urinary tract stone after extracorporeal shock wave lithotripsy (ESWL). Methods: A total of 100 patients with upper urinary tract stones admitted from January 2014 to January 2015 were selected as the control group and the experimental group, 50 cases in each group. Both groups received ESWL treatment. The control group The patients were treated with Nephrite Granules, and the patients in the experimental group were treated with oral tamsulosin hydrochloride sustained-release capsules. The clinical efficacy of auxiliary tamponade after ESWL in patients with upper urinary tract stones was compared between the two groups. Results: After treatment, systolic blood pressure (122.06 ± 12.43) mm Hg and diastolic blood pressure (75.26 ± 5.43) mm Hg in the experimental group were slightly lower than those in the control group (128.39 ± 21.32 mm Hg and 77.36 ± 7.45 mm Hg, respectively) In the experimental group, the stone elimination rate after treatment was 88.00%, which was significantly higher than that in the control group (70.00%). The clinical observation indexes in the experimental group were significantly better than those in the control group (P <0.05). CONCLUSION: The tamsulosin hydrochloride sustained-release capsules are superior to the traditional Chinese medicine of kidney stone granules in the treatment of patients with upper urinary tract stone after extracorporeal shock wave lithotripsy (ESWL).