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区别原发性(或特发性)系统性红斑狼疮(SLE)与药源性 SLE 尚无明确的标准。后者更易发生在老人中,极少引起肾脏及神经系统损害,血清抗核抗体(ANA)阳性,缺乏自身 DNA 抗体,通常在停药后狼疮样综合征可迅速消失。作者报道1例因使用降压药长压定而引起胸膜及心包渗出液和 ANA 阳性患者。患者78岁,女性。患高血压病,药物控制血压稳定。因右第二趾坏疽而手术,术后血压难以控制,采用速尿、氨酰心安及长压定治疗,曾查 ANA 阴
There is no definitive standard for distinguishing between primary (or idiopathic) systemic lupus erythematosus (SLE) and drug-induced SLE. The latter is more likely to occur in the elderly, rarely cause kidney and nervous system damage, positive serum anti-nuclear antibody (ANA), the lack of their own DNA antibodies, lupus-like syndrome usually disappear rapidly after withdrawal. The authors reported a case of pleural and pericardial exudate and ANA-positive patients due to long-term hypotension with antihypertensive drugs. Patient 78 years old, female. Hypertension, drug control of blood pressure and stability. Due to right second toe gangrene and surgery, postoperative blood pressure is difficult to control the use of furosemide, Atenolol and long-pressure treatment, had checked ANA negative