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目的探讨婴儿肝炎综合征的病因、临床表现及预后。方法对确诊为婴儿肝炎综合征的32例病例资料进行临床观察及随访分析。结果病原学检查结果提示病毒感染,尤其巨细胞包涵体病毒感染最多见,占59%,乙型肝炎病毒感染占第2位,为25%;巨细胞包涵体病毒感染可引起黄疸、肝肿大、肝功能异常以及胆道闭锁、溶血,且病情重,易致肝硬化,日后有可能引起智力及听力障碍等后遗症。结论巨细胞包涵体病毒感染是婴儿肝炎综合征的主要病因。早发现、早诊断及早治疗是避免发展成为肝硬化、降低死亡率和减轻后遗症的关键。
Objective To investigate the etiology, clinical manifestations and prognosis of infant hepatitis syndrome. Methods 32 cases of infantile hepatitis syndrome diagnosed as clinical data and follow-up analysis. Results The results of etiological examination suggested that the virus infection, in particular, the most common viral infection of cytomegalovirus, accounting for 59%, hepatitis B virus infection accounted for 2, was 25%; giant cell inclusion virus infection can cause jaundice, hepatomegaly , Liver dysfunction and biliary atresia, hemolysis, and severe illness, easily lead to cirrhosis, the future may cause mental and hearing disorders and other sequelae. Conclusion Cytomegalovirus infection is the main cause of infant hepatitis syndrome. Early detection of early diagnosis and early treatment is the key to avoiding the development of cirrhosis, reducing mortality and reducing sequelae.