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目的分析保乳术与改良根治术治疗早期乳腺癌的疗效。方法 90例早期乳腺癌患者,随机分为甲乙两组,各45例。甲组患者接受改良根治术治疗,乙组患者接受保乳术治疗。对比分析两组患者的治疗效果(乳房外形评价)、手术各项指标(术中出血量、术后并发症、手术时间、引流量)和远期疗效复发率、转移率、3年生存率。结果乙组患者外形优良率明显高于甲组,差异有统计学意义(P<0.05)。两组患者的复发率、转移率、3年生存率比较差异无统计学意义(P>0.05)。乙组患者并发症发生率及手术各项指标均明显优于甲组,差异有统计学意义(P<0.05)。结论保乳术与改良根治术治疗早期乳腺癌均有一定的疗效,从近期效果来看,保乳术更佳,其乳房外形优良率高,且术中出血量少,手术时间短,术后并发症少。但从远期疗效来看,两种手术方式复发率、转移率、3年生存率相似,在临床治疗时可以根据患者情况进行选择。
Objective To analyze the effect of conservative surgery and modified radical mastectomy on early breast cancer. Methods Ninety patients with early breast cancer were randomly divided into two groups (A and B), 45 cases each. Group A patients underwent modified radical mastectomy, patients in Group B underwent breast-conserving surgery. The therapeutic effect (breast shape evaluation), operation indexes (intraoperative blood loss, postoperative complications, operation time, drainage volume) and long-term efficacy recurrence rate, metastasis rate and 3-year survival rate were compared between the two groups. Results The excellent shape rate of patients in group B was significantly higher than that in group A, the difference was statistically significant (P <0.05). There was no significant difference in recurrence rate, metastasis rate and 3-year survival rate between the two groups (P> 0.05). The incidence of complications and the indexes of operation in group B were significantly better than those in group A, with significant difference (P <0.05). CONCLUSION: Both breast-conserving surgery and modified radical mastectomy have a certain curative effect on early-stage breast cancer. From the short-term results, breast-conserving surgery is better, breast shape is excellent and the rate of intraoperative bleeding is less, the operation time is short, Less complications. However, from the long-term efficacy, the recurrence rate of two surgical methods, the transfer rate, 3-year survival rate similar to the clinical treatment can be selected according to the patient’s condition.