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目的观察护理干预对减轻侵蚀性葡萄胎化疗患者不良反应的影响。方法选取医院收治的侵蚀性葡萄胎患者100例,按是否愿意接受临床护理干预分为观察组和对照组,每组50例。对照组采取常规护理,观察组在常规护理基础上采取临床护理干预,比较2组护理前后焦虑情况及治疗后消化道反应情况。结果 2组患者在治疗前不同程度焦虑情况比较,差异均无统计学意义(P>0.05);治疗后,在明显焦虑、一般焦虑及无焦虑方面观察组与对照组差异有统计学意义(P<0.01);2组治疗后恶心呕吐、腹痛腹泻及口腔溃疡单一项目比较,差异无统计学意义(P>0.05);2组治疗后消化道总反应比较,差异有统计学意义(P<0.01)。结论护理干预对减轻侵蚀性葡萄胎化疗患者不良反应的影响效果显著,具有临床推广意义。
Objective To observe the effect of nursing intervention on alleviating adverse reactions in patients with invasive hydatidiform mole chemotherapy. Methods 100 patients with invasive hydatidiform mole admitted to the hospital were divided into observation group and control group according to whether they were willing to accept clinical nursing intervention and 50 patients in each group. The control group to take routine care, the observation group on the basis of routine care to take clinical nursing intervention, compared anxiety before and after care in the two groups and after treatment of gastrointestinal reactions. Results There was no significant difference in anxiety between the two groups before treatment (P> 0.05). After treatment, there was significant difference between the observation group and the control group in terms of obvious anxiety, general anxiety and no anxiety (P <0.01). There was no significant difference between the two groups in the single item of nausea and vomiting, abdominal pain and diarrhea and oral ulcer (P> 0.05). There was significant difference in the total digestive tract response between the two groups after treatment (P <0.01) ). Conclusion Nursing interventions have a significant effect on alleviating the adverse reactions of patients with invasive hydatidiform mole chemotherapy and have clinical significance.