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甲状旁腺功能减退的传统治疗包括维生素D及饮食中钙的补充。这种疗法增进了肠内对钙的吸收,使血清钙的水平恢复正常。然而由于血清钙增加趋向正常,发生明显的高尿钙,结果引起维生素D治疗的并发症-肾石病。作者用氯噻酮(Chlorthalidone)加限盐饮食对7名甲状旁腺功能减退病人进行25月治疗,平均24小时排钙由179mg减至88mg(P<0.001),而平均血清钙由每dl 8.2mg增至9.3 mg(P<0.05)。作者研究结果表明:象噻喹类这种利尿剂并不需要甲状旁腺激素便能减少尿中钙。本组病人皆有重度
Traditional treatments for hypoparathyroidism include vitamin D and dietary calcium supplements. This therapy increases intestinal absorption of calcium and normalizes serum calcium levels. However, due to the increase in serum calcium tends to normal, significant hypercalciuria occurred, the result of vitamin D treatment complications - nephrolithiasis. The authors treated seven patients with hypoparathyroidism for 25 months with a chlorthalidone plus salt restriction diet, with a mean 24-hour discharge of calcium from 179 mg to 88 mg (P <0.001), while mean serum calcium was raised from 8.2 to 8.2 mg to 9.3 mg (P <0.05). The authors study showed that: diuretics like thiazide do not need parathyroid hormone can reduce urinary calcium. This group of patients are all severe