应用纤维胃镜对有上消化道症状的患儿进行胃粘膜组织学、尿素酶检测。对证实有幽门螺杆菌（Hp）感染的40例胃炎、十二指肠炎及消化性溃疡病人给予奥美拉唑、克拉霉素、甲硝唑口服治疗10d，全部病人停药后1mo复查胃镜。结果显示Hp根除率90％，临床症状基本缓解；药物不良反应32．5％。治疗后镜下胃粘膜炎症好转明显，病理组织学检查2／3病人改善。 Application of fiber endoscopy in children with upper gastrointestinal symptoms of gastric mucosa, urease test. Forty cases of gastritis, duodenitis and peptic ulcer confirmed to have Helicobacter pylori (Hp) infection were orally treated with omeprazole, clarithromycin and metronidazole for 10 days. All the patients underwent gastroscopy 1 month after drug withdrawal. The results showed that the eradication rate of Hp was 90%, and the clinical symptoms were basically relieved. The adverse drug reaction was 32.5%. After treatment, gastric mucosal inflammation improved significantly, 2/3 of patients with histopathological improvement.