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1973年我院寄生虫学教研室负责人在原上海寄生虫病研究所工作时,根据血吸虫卵肉芽肿病变属迟发型变态反应的原理,首先证明,家兔肌注醋酸可的松(ACT,25～50mg/兔/日)后,可较对照组增高血吸虫卵获得量55％。1983～1984年,我院寄生虫学教研室进一步深入研究,结果证明:感染兔经肌注ACT后,其特异性抗体水平下降,肝组织内血吸虫卵的病变减弱,肝组织内虫卵活性及反应不受影响;肝内虫卵的获得量在20mg/兔/日组为对照组的2.3倍,在15mg/兔/
1973 Department of Parasitology, the head of the Department of Parasitic Diseases, Shanghai Institute of the original work, according to the principle of schistosomiasis egg granulomatosis is a late-onset allergy, first demonstrated that intramuscular injection of cortisone acetate (ACT, 25 ~ 50mg / rabbit / day), compared with the control group increased schistosome eggs obtained 55%. From 1983 to 1984, further research was carried out in the Parasitology Department of our hospital. The results showed that the level of specific antibodies decreased after transfection of rabbit intramuscularly with ACT, the pathological changes of schistosome eggs in liver tissues were weakened, Not affected; the amount of intrahepatic egg obtained in the 20mg / rabbit / day group 2.3 times the control group, at 15mg / rabbit /