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近几年,用多支链氨基酸注射液静脉滴注治疗肝昏迷,作为一种新的疗法在国外得到承认。两年来,我们在门脉性肝硬化昏迷的患者中,选择性地应用了静滴多支链氨基酸疗法,在改善患者昏迷程度方面,取得显著效果,现报道如下。 临床资料 一般资料 20例有门脉性肝硬化病史的肝昏迷患者,其中男性16例,女性4例,年龄24～68岁,平均年龄46.5岁,平均病史8.6年,平均体重58.4公斤。20例患者中,肝功能尚好的有15例,腹水、黄疸、血清白蛋白减少的有5例。全部患者在接受多支链氨基酸治疗前具有:1.血氨值升高;2.脑电图提示慢波;3.昏迷程度在Ⅰ期～Ⅳ期之间。
In recent years, the treatment of hepatic coma with multi-branched-chain amino acid injection has been recognized abroad as a new therapy. In the past two years, we have selectively used intravenous multi-branched-chain amino acid therapy in patients with coma of portal cirrhosis and achieved significant results in improving the patient’s coma, which are reported below. Clinical data General Information 20 cases of liver cirrhosis patients with history of coma, including 16 males and 4 females, aged 24 to 68 years, mean age 46.5 years, with a mean history of 8.6 years, with an average weight of 58.4 kg. Twenty patients had good hepatic function in 15 cases, ascites, jaundice and serum albumin in 5 cases. All patients received multi-branched-chain amino acid therapy before: 1. Blood ammonia value increased; 2. EEG slow wave; 3. Coma degree between Ⅰ to Ⅳ.