本文报告三例年轻女病人,开始表现为视神经炎,后来在周围血液中都找到狼疮细胞而明确诊断。例1先有眼外肌无力,游走性关节炎。四个月后右眼球后疼痛,视力丧失,随后左眼亦视力丧失,出现视神经乳头水肿,并有火焰状出血及视网膜水肿。用强地松治疗数天后右眼周边视力好转,但留有扩大的中心盲点。三个月后发生严重视神经萎缩,一年后因多发性出血死亡。例2突然发生左眼无痛性失明,视神经乳头显轻度水肿及视网膜血管充血。用强地松治疗,周边视力恢复,但几周后视力又丧失,出现严重的视神经萎缩。三年后发生截瘫,并有 This article reports three cases of young female patients, began to manifest as optic neuritis, and later found in the surrounding blood lupus cells and a clear diagnosis. Example 1 First, extraocular muscle weakness, migratory arthritis. After four months after the right eye pain, loss of vision, followed by left eye also loss of vision, optic disc papillary edema, and flaming bleeding and retinal edema. After several days of treatment with prednisone, visual acuity improved in the right eye, but with an enlarged center blind spot. Severe optic atrophy occurred three months later and died of multiple bleeds one year later. Example 2 Sudden left eye painless blindness, optic nerve head was mild edema and retinal vascular congestion. Treatment with prednisone, peripheral vision recovery, but a few weeks after the loss of vision, severe optic atrophy. Three years after paraplegia, and there