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检测了106例各型病毒性肝炎血清氨基酸,发现蛋氨酸均显著升高,急性肝炎患者脯氨酸、丙氨酸和缬氨酸显著下降,其余13种氨基酸与正常对照组比较无差异.急性期与恢复期亦无差异(P>0.05);慢活肝患者酪氨酸、苯丙氨酸亦显著增高;重症肝炎患者支链氨基酸显著下降,芳香族等12种氦基酸显著增高.BCAA/AAA克分子比值慢活肝、重症肝炎明显低于正常对照组(P<0.05),重症肝炎降低最显著(P<0.01),测定血清氨基酸对了解病情,预后及转归有一定的临床意义.
A total of 106 cases of various types of viral hepatitis serum amino acids found methionine were significantly increased, acute hepatitis patients proline, alanine and valine significantly decreased, the remaining 13 kinds of amino acids compared with the normal control group no difference in acute phase (P> 0.05). The contents of tyrosine and phenylalanine in patients with chronic liver disease were significantly higher than those in patients with severe hepatitis, while those in patients with severe hepatitis were significantly decreased (P <0.05), severe hepatitis was the most significant decrease (P <0.01). Determination of serum amino acids was of clinical significance to understand the disease, prognosis and prognosis.