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目的：探讨完全缓解期急性白血病常规化疗及G－CSF对PBSC的动员效果及最佳采集时机。方法：以外周血WBC及单核细胞绝对值为参数，观察化疗后不同时期的CFU－GM值。结果：化疗及G－CSF均有明显的PBSC动员作用，两者联合效果更佳。结论：WBC恢复至（2．0～4．5）×109／L时为最佳PBSC采集时机。单核细胞绝对值对PBSC动员效果有预测作用。
OBJECTIVE: To investigate the effect of conventional chemotherapy with complete remission acute leukemia and G-CSF on mobilization and optimal timing of PBSC. Methods: Absolute values of WBC and monocytes in peripheral blood were used as parameters to observe the CFU-GM values in different periods after chemotherapy. Results: Both chemotherapeutic and G-CSF have obvious mobilization of PBSC, and the combination of the two is better. Conclusion: WBC recovery to (2.0 ~ 4.5) × 109 / L is the best time for PBSC collection. Monocyte absolutes have a predictive effect on mobilization of PBSC.