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急迫性尿失禁是逼尿肌收缩并伴有短暂警告所致的尿流失控综合征。常见于神经原性膀胱、膀胱异物、膀胱肿瘤、膀胱炎或前列腺炎,但尚有部分病例不能解释,其病理生理学还不清楚。现在认为,逼尿肌不稳定,逼尿肌反射亢进,尿道不稳定(膀胱充盈时尿道压>15CmH_2O)和膀胱感觉差等都是急迫性尿失禁的必要条件。最近研究指出,膀胱的感觉可能由二种感觉器调节:一是压力感受器,位于底三角和后尿道,对膀胱内压微小变化敏感,可能起膀胱充盈的早期警告系统作用;二是张力感受器,位于膀胱体机层,
Urge incontinence is a detrusor out of control syndrome with detrusor contractions accompanied by brief warnings. Common in neurogenic bladder, bladder foreign body, bladder cancer, cystitis or prostatitis, but there are still some cases can not explain the pathophysiology is unclear. Now that detrusor instability, detrusor hyperreflexia, urethral instability (urinary bladder pressure urinary bladder pressure> 15CmH_2O) and poor bladder sensation are all the necessary conditions for urge incontinence. Recent studies have shown that bladder sensation may be regulated by two sensory receptors: the baroreceptor, located in the bottom of the triangle and the posterior urethra, is sensitive to small changes in bladder pressure and may serve as an early warning system for bladder filling; and second, Located in the cystic layer,