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目的探讨柳氮磺吡啶肠溶片导致不良反应的临床表现,为该药在临床安全、合理的使用提供参考。方法搜集2015年河南中医学院第一附属医院上报的柳氮磺吡啶肠溶片导致的不良反应报告合计4例,对其临床表现及预后进行汇总分析。结果柳氮磺吡啶肠溶片所致不良反应主要体现在消化道反应方面。结论增强用药安全意识,做好用药教育,预防不良反应发生。
Objective To investigate the clinical manifestations of sulfasalazine enteric-coated tablets in patients with adverse reactions and to provide a reference for its safe and rational use in clinic. Methods A total of 4 cases of adverse reactions caused by sulfasalazine enteric-coated tablets were collected from the First Affiliated Hospital of Henan University of Traditional Chinese Medicine in 2015. Their clinical manifestations and prognosis were summarized. Results Sulfasalazine enteric-coated tablets caused by adverse reactions mainly reflected in the gastrointestinal reactions. Conclusions It is necessary to enhance awareness of medication safety, do medication education and prevent adverse reactions.