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了解并发脑出血、脑梗死(CI)和心肌梗死(MI)的高血压患者降压药的药物利用情况。方法运用药物流行病学的研究方法,对脑出血、CI和MI患者的抗高血压药的药物利用情况进行了横断面调查。结果住院前患者所服用过的降压药中老的复方制剂居首位(73.7%),β受体阻断剂和利尿剂占少数,分别为23.0%和1.1%。而住院期间患者所服用的降压药则以血管紧张素转换酶抑制剂(ACEI)和钙拮抗剂为主,分别是45.9%和35.6%,而复方制剂则为8.4%。结论住院前患者所服用过的降压药中仍以老的复方制剂为主,但是与80年代的利用情况相比有所下降。由JNCV所推荐的一线降压药———β受体阻断剂和利尿剂占少数;住院期间患者所服用的降压药以ACEI和钙拮抗剂为主
To understand the use of antihypertensive drugs in hypertensive patients with cerebral hemorrhage, cerebral infarction (CI) and myocardial infarction (MI). Methods A cross-sectional survey of drug use of antihypertensive agents in patients with cerebral hemorrhage, CI and MI was conducted using a pharmacoepidemiological approach. Results The hospitalized patients took the first place (73.7%) of the antihypertensive drugs in combination with the old ones, while the β-blockers and diuretics accounted for a minority of 23.0% and 1.1% respectively. The antihypertensive drugs taken by patients during hospitalization were mainly angiotensin converting enzyme inhibitors (ACEIs) and calcium antagonists, which were 45.9% and 35.6%, respectively, compared with 8.4% for compound preparations . Conclusions Antihypertensive drugs taken before hospitalization are still predominantly in the form of an older compound, but they have declined in comparison with the utilization in the 1980s. The first-line antihypertensive drugs recommended by JNCV --- β receptor blockers and diuretics accounted for a minority; patients taking antihypertensive drugs in patients with ACEI and calcium-based antagonists