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１９９２～１９９５年，在广州市珠海区和海康市各选择１个既往登革热（简称ＤＦ）流行区和非流行区作为ＤＦ监测点，并对省内临床疑似ＤＦ病人进行监测。从１０４份疑似ＤＦ患者急性期血清分离出３４株病毒。分离阳性率为３２．６９％，分别是１９９３年的登革２型和１９９５年的登革１型。１３１６只蚊分为１１６组，经Ｃ６／３６白纹伊蚊细胞培养和单克隆抗体间接免疫荧光试验检测，全部未分离出ＤＦ病毒。１９８份疑似ＤＦ患者血清作登革ＩｇＧ抗体（ＤＶ－ＩｇＧ）检测，检出阳性５５份，检出率为２７．７８％，２份是１９９３年同一患者双相血清。５３份是１９９５年单份血清，与各型ＤＦ病毒抗原呈高度广泛交叉反应，不能判定流行型。５例病后约１００天的ＤＦ患者其ＩｇＧ抗体滴度普遍下降。检测９７２份健康人血清ＤＶ－ＩｇＧ，检出１３１份阳性，检出率为１３．４％，阳性抗体滴度大多在１∶４０。但１９９４年抗体滴度１∶８０～１∶１６０的有１９份，明显高于其它年。
From 1992 to 1995, one epidemic area and one non-epidemic area of dengue fever (dengue fever) in Zhuhai district and Haikang city of Guangzhou were selected as DF monitoring points, and the clinical suspected DF patients in the province were monitored. Thirty-four viruses were isolated from 104 acute cases of suspected DF patients. The positive rate of separation was 32.69%, which were dengue 2 in 1993 and dengue 1 in 1995 respectively. 1316 mosquitoes were divided into 116 groups and tested by C6 / 36 Aedes albopictus cell culture and indirect immunofluorescence assay with monoclonal antibody, all of which did not isolate DF virus. A total of 198 suspected DF patients were tested for dengue IgG antibody (DV-IgG), and 55 were positive, the detection rate was 27.78%. Two of them were biphasic sera from the same patient in 1993. 53 copies of a single serum in 1995, with a wide range of cross-reactivity with various types of DF virus antigen, can not determine the epidemic. Five patients with DF in about 100 days after the general decline in its IgG antibody titer. Serum DV-IgG was detected in 972 healthy volunteers. 131 positive samples were detected, the detection rate was 13.4%, and the positive antibody titers were mostly 1:40. However, 19 antibody titers 1:80 to 1:160 in 1994 were significantly higher than those in other years.