Breakage, comminution, crushing and fragmentation of brittle solids under dynamic impacts are an important applied mechanics and rock mechanics problem. In civil engineering applications, impact-induced-fragmentation relates to crushing of rock mass during mining process, tunneling, and aggregate production. The main objective of this paper is to outline some of our recent experimental, analytical and numerical efforts in studying the dynamic fragmentation process in brittle particle. First, an analytical solution of a solid sphere compressed dynamically between two rigid flat platens is derived analytically. Secondly, a sequence of double impact tests on spheres were conducted using an impactor Dynatup 8250 at HKUST, with both impact velocity and contact force at the impactor measured accurately. Finally, a newly developed computer program, DIFAR, is used to investigate the mechanism of dynamic fragmentation. The paper will summarize and discuss briefly all three aspects of our comprehensive approach.