目的了解宫内缺氧对新生儿神经行为和脑反应性功能的影响。方法应用中国新生儿２０项行为神经测定法和近红外光谱测定技术，对有明确宫内缺氧史的５９例新生儿（依有无神经系统症状分２组）进行检测，并设正常对照组３４例进行对比。结果有宫内缺氧史的新生儿其神经行为评分明显低于对照组，主要减分项目为行为能力和主动肌张力。脑氧合功能检测基础氧合状态降低，脑反应性功能减弱。宫内缺氧组与对照组比较差异显著。有神经系统症状组与无神经系统症状组间比较无显著性差异。结论宫内缺氧对新生儿神经行为和脑反应性功能有影响，临床应予以关注和适当干预 Objective To investigate the effects of intrauterine hypoxia on the neurobehavioral and cerebral reactivity in neonates. Methods Twenty newborns with behavioral neuroimaging and near-infrared spectroscopy were used in this study. Fifty-nine neonates with a history of intrauterine hypoxia (divided into two groups with no neurological symptoms) were divided into two groups: normal control group 34 cases were compared. Results The neonatal intrauterine hypoxia had significantly lower neurobehavioral scores than the control group. The main items were behavioral abilities and active muscle tone. The basis of cerebral oxygenation decreased the state of oxygenation, reduced brain reactivity. Intrauterine hypoxia group compared with the control group significant difference. There was no significant difference between the nervous system symptom group and no neurological symptom group. Conclusion Intrauterine hypoxia has an impact on the neurobehavioral and cerebral reactivity of neonates, and clinical attention should be given and appropriate intervention