咳必清系化学合成的苯环戊烷羧酸类镇咳药。文献报道副作用很少,对小白鼠、家兔及狗的致死量分别为27mg/kg、25mg/kg、64mg/kg。但咳必清多为糖衣片剂,易被小儿误服而致中毒。中毒后常表现为皮肤潮红、瞳孔散大、口干腹胀、脉数等阿托品样反应。文献记载严重者可出现肢体强直、癫痫样发作及昏迷,甚至死亡。有关咳必清中毒的临床表现及处理方法,文献资料上记载甚少。我院儿科曾收治咳必清中毒小儿5例,经及时有效的处理全部治愈,兹作如下介绍: 咳必清中毒的临床表现、 Penehyclidine is a chemically synthesized benzene cyclopentane carboxylic acid antitussive. Reported in the literature few side effects on mice, rabbits and dogs were 27mg / kg, 25mg / kg, 64mg / kg. However, cough must be more than sugar-coated tablets, easy to be mistaken for children poisoning. After poisoning often manifested as flushing, mydriasis, dry mouth, abdominal distension, a pulse-like atropine-like reaction. Documented severe cases may appear limb rigidity, epileptic seizures and coma, and even death. On the cough must clear poisoning clinical manifestations and methods of treatment, documented little documented. Pediatrics in our hospital had received cough poisoning poisoning in children in 5 cases, the timely and effective treatment of all cured, hereby make the following introduction: The clinical manifestations of cough clear poisoning,