特利加压素(Terlipressin,Glypressin,,三甘氨酰基赖氨酸加压素)为一种新型的加压素类似物,可长期的使血管收缩。作者等对29例肝硬化伴食管静脉曲张破裂出血者,在常规治疗的基础上,随机接受本品2mg或安慰剂静脉注射,每4小时1次,直至出血得以控制。治疗持续8小时。然后,每隔4小时静注本品1mg或安慰剂4次。输血等常规治疗措施两组病人相似。 29例患者有31次食道静脉曲张出血,经本品治疗15次,安慰剂16次。治疗组出血控制率60％(9/15),安慰剂组为37％ Terlipressin (Glypressin, triglycyl-lysine vasopressin) is a novel vasopressin analog that vasoconstricturizes over the long term. The author of 29 cases of cirrhosis with esophageal variceal bleeding in the conventional treatment, based on randomized to receive 2mg of this product or placebo intravenous injection every 4 hours until the bleeding can be controlled. Treatment lasts 8 hours. Then, intravenous injection of 1mg or placebo 4 hours every 4 hours. Transfusion and other conventional treatment measures similar to the two groups of patients. Thirty-nine patients had esophageal variceal hemorrhage, treated with this product 15 times and placebo 16 times. The bleeding rate was 60% (9/15) in the treatment group and 37% in the placebo group