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作者采用小淋巴细胞毒素中毒技术,用对 HLA-A、B、C 抗原有特异性的 HLA 抗血清对4例特发性儿童卒中患儿进行主要组织相容性(MHC)Ⅰ级抗原测定。结果表明,4例患儿均有人类白细胞抗原(HLA)-B_(51),而对照组3例非特异性卒中综合征(烟雾病、脑梗塞、孤立性脑血管炎)及3例诊断为皮肌炎、复发性肌球蛋白尿和原发性癫痫大发作患儿均未显示 HLA-B_(51),两组间差异显著。作者指出,HLA-B_(51)在普通人群中的发生率相对
The authors used the technique of small lymphocytotoxicity to determine the primary histocompatibility (MHC) class I antigen in four children with idiopathic childhood stroke using HLA antisera specific for the HLA-A, B, C antigens. The results showed that all four patients had human leukocyte antigen (HLA) -B_ (51), while the control group had three cases of nonspecific stroke syndrome (moyamoya disease, cerebral infarction, solitary cerebrovascular disease) and three cases diagnosed as skin Myositis, recurrent myosinuria and primary epileptic seizures did not show HLA-B_ (51), the difference was significant between the two groups. The authors note that the incidence of HLA-B_ (51) in the general population is relative