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目的提高对药物性肝炎的认识。方法采用回顾性分析,根据服药史、临床表现、肝功能、病原学标志物综合判断。结果126例药物性肝炎患者中,中草药(27.7%),抗结核药(24.6%),抗感染药(11.9%),抗精神病药(9.5%),抗甲状腺药(8.7%)。黄疸性肝炎(73%),重型肝炎(10.3%),3例病人因肝功能衰竭死亡。
Objective To improve the understanding of drug-induced hepatitis. Methods The retrospective analysis, based on medication history, clinical manifestations, liver function, pathogenic markers comprehensive judgment. Results Among the 126 patients with drug-induced hepatitis, Chinese herbal medicine (27.7%), anti-TB drug (24.6%), anti-infective drug (11.9%), antipsychotic drug (9.5%) and antithyroid drug (8.7%). Jaundice hepatitis (73%), severe hepatitis (10.3%), and 3 patients died of liver failure.