A clinical study was conducted on the anti-aging effects of an emulsion containing carnosine and centella asiatica extract to provide a reference for the evaluation and development of anti-aging cosmetics. Sixty healthy females, aged 35～60, were divided into the test sample and placebo groups. Skin elasticity and wrinkles of the participants were analyzed before they used the emulsion and after they used it for 8 weeks.Instrument measurement results showed that after 8 weeks, skin elasticity and wrinkles in the members of the test sample group improved relative to those of the placebo group. Clinical effect assessment results showed that subjects did not experience adverse skin reactions, and their skin wrinkles showed improvement. Self-assessment results showed that the score of the total satisfaction of the test sample was 4.3, and 100％ subjects are satisfied with the test sample. Emulsion containing carnosine and centella asiatica extract has a certain anti-aging effect.