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本课题对5-氟脲嘧啶白蛋白微球(5-FUAS)的较佳制备条件、体内分布及其物理稳定性进行了研究。经L_9(3~4)正交实验设计法研究表明,在微球制备过程中,搅拌乳化时间对微球
The preparation of 5-fluorouracil-loaded albumin microspheres (5-FUAS) was studied in this thesis. The preparation conditions, in vivo distribution and physical stability of 5-fluorouracil albumin microspheres were investigated. The L_9 (3 ~ 4) orthogonal experimental design studies show that in the preparation of microspheres, mixing emulsification time on the microspheres