Wegener肉芽肿病(WG)是一种原因不明的多系统疾病,其特征为坏死性肉芽肿性血管炎,常累及上呼吸道、肺和局灶性肾小球肾炎,但泌尿生殖器的表现报道甚少。作者回顾分析从1973～1993年间在门诊或病房所见的80例WG。其中男45例,女35例,诊断时平均年龄50±14岁。在排除了其它原因,尤其是感染和药物副作用,包括环磷酰胺相关的膀胱炎后,8例被确认有与WG相关的泌尿生殖器表现。 Wegener’s granulomatosis (WG) is a multi-system disease of unknown cause characterized by necrotizing granulomatous vasculitis, often involving the upper respiratory tract, lungs, and focal glomerulonephritis but reports of genitourinary manifestations less. The authors reviewed 80 cases of WG seen in outpatients or wards from 1973 to 1993. There were 45 males and 35 females with an average age of 50 ± 14 years at diagnosis. After excluding other causes, especially infection and side effects of drugs, including cyclophosphamide-related cystitis, 8 cases were confirmed to have genitourinary manifestations associated with WG.