内皮素（ＥＴ）作为机体在严重缺氧缺血等应激状态下的一种内源性致病因子日益受到重视。本文通过对３８例新生儿呼吸衰竭（简称呼衰）患儿测定血浆ＥＴ水平，同时监测动态肺动能，以探讨新生儿呼衰与ＥＴ及肺功能的关系。对象和方法一、对象　１．新生儿呼衰组，１９９６年１ Endothelin (ET), as an endogenous virulence factor under the condition of severe hypoxic-ischemic stress, is gaining more and more attention. In this paper, 38 cases of neonatal respiratory failure (referred to as respiratory failure) in children with plasma ET levels, and dynamic pulmonary motility monitoring to explore neonatal respiratory failure and ET and pulmonary function. Objects and methods First, the object 1. Neonatal respiratory failure group, 1996 1