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目的了解砷中毒皮肤病地域流行状况及主要临床表现。方法对高发地区水源进行砷含量测定，调查高发地区人群皮肤损害表现。结果调查１１２４例中，皮肤受累２６５例（２７．０７％）。主要表现为色素脱失、色素沉着及掌跖过度角化，具此三联症者７２例（７．３５％）。结论砷性皮肤改变主要发生在长期高坤环境下生活的居民中，主要临床表现为脱色、着色和过度角化。
Objective To understand the endemic situation and main clinical manifestations of arsenic poisoning dermatosis. Methods Determination of arsenic in water sources in high incidence areas to investigate the performance of skin lesions in high incidence areas. Results 1124 cases of skin involvement in 265 cases (27.07%). Mainly as hypopigmentation, hyperpigmentation and metatarsal hyperkeratosis, with this triad 72 cases (7.35%). Conclusion Arsenic skin changes mainly occur in residents living under long-term high-kun environment. The main clinical manifestations are bleaching, coloration and hyperkeratosis.