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目的 :观察低分子量肝素 (LMWH)治疗急性脑梗死的疗效。方法 :用LMWH腹壁皮下注射治疗急性脑梗死 48例。以低分子右旋糖酐静脉滴注 3 9例作为对照。结果 :LMWH组与对照组的显效率分别为 72 92 %与 46 15 % ( P <0 0 5 ) ,总有效率分别为 89 5 8%与 76 92 % (P <0 0 5 ) ,LMWH组功能恢复明显优于对照组 (P <0 0 5 )。LMWH组 2 7例治疗后与治疗前做CT检查 ,显示脑梗死灶体积明显缩小 (P <0 0 1)。结论 :LMWH对急性脑梗死有较稳定的疗效 ,简便易行。
Objective: To observe the effect of low molecular weight heparin (LMWH) on acute cerebral infarction. Methods: Forty-eight cases of acute cerebral infarction were treated with subcutaneous injection of LMWH abdominal wall. Low molecular dextran intravenous infusion of 39 cases as a control. Results: The effective rates of LMWH group and control group were 72 92% and 46 15% (P 0 05), respectively. The total effective rates were 89 58% and 76 92% respectively (P 0 05) Function recovery was significantly better than the control group (P <0 05). Twenty-seven patients in the LMWH group had CT examination before and after treatment, showing that the volume of cerebral infarction was significantly reduced (P <0.01). Conclusion: LMWH has a more stable curative effect on acute cerebral infarction, which is simple and easy to operate.