为定量研究庆大霉素(Gen)和丁胺卡那霉素(Amk)的肌松作厢,进行了小鼠攀网、小鸡垂头和大鼠膈神经一膈肌离体标本的研究。结果表明,Gen和Amk的肌松作用与简箭毒碱(Tub)相似,均呈非去极化型,Gen的肌松强度约为Amk的2倍。Gen的神经肌接头阻滞作用几呈全或无型反应,其S值明显大 In order to quantitatively study the muscle relaxation of gentamicin (Gen) and amikacin (Amk), we studied the cloning, chipping of the chick and the isolated phrenic nerve in rat diaphragm. The results showed that both Gen and Amk had non-depolarizing muscle relaxants similar to those of Tuberone, and Gen had a muscle relaxant of about 2 times that of Amk. Gen neuromuscular block several effects were all or no reaction, the S value was significantly larger