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超声检查以其无创、可重复、结果可靠等优势已成为胎儿异常筛查最常用的手段,除可观察到一些直观的异常如唇裂、手足畸形及各个系统发育异常造成的畸形,产科超声检查还可发现被认为是正常变异的一些现象。这些超声表现异于胎儿正常的解剖结构,但不同于胎儿的解剖结构畸形,但有这些超声表现的胎儿,单倍体异常的危险性增高,这些超声表现被称为胎儿“软标志”。
Ultrasonography has become the most commonly used method for fetal abnormality screening because of its advantages of non-invasive, reproducible and reliable results. In addition to some visual abnormalities such as cleft lip, hand-foot deformities and deformities caused by various system dysplasia, obstetric ultrasonography Something that is considered to be normal can be found. These sonographic findings are different from the normal anatomy of the fetus, but different from the anatomical anomalies of the fetus, but the fetus with these ultrasound findings is at an increased risk of haploidentical abnormalities and these ultrasound findings are called fetal “soft signs” .