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目的分析有创和无创序贯性机械通气在治疗重症肺炎合并呼吸衰竭病症的临床效果。方法将68例重症肺炎合并呼吸衰竭患者随机分为序贯组和对照组各34例。序贯组患者给予从有创到无创的序贯性机械通气的模式;对照组进行常规有创机械通气。结果治疗后2组患者的Pa O2、Pa CO2、p H值均达到了正常水平,与治疗前比较差异均有统计学意义(P<0.05),但治疗后上述指标组间比较差异无统计学意义(P>0.05)。序贯组呼吸机相关肺炎发生率低于对照组,撤机成功率高于对照组,差异均有统计学意义(P<0.05)。结论有创与无创序贯性机械通气在治疗重症肺炎合并呼吸衰竭的病症上有明显改善的临床治疗效果。
Objective To analyze the clinical effects of invasive and noninvasive sequential mechanical ventilation in the treatment of severe pneumonia complicated with respiratory failure. Methods Sixty-eight patients with severe pneumonia complicated with respiratory failure were randomly divided into sequential group and control group, 34 cases each. Patients in the sequential group were given sequential mechanical ventilation from invasive to noninvasive; the control group received conventional invasive mechanical ventilation. Results PaO2, Pa CO2 and p H values in both groups after treatment reached the normal levels, with statistical significance (P <0.05), but there was no significant difference between the two groups after treatment Significance (P> 0.05). Sequential group of ventilator-associated pneumonia incidence was lower than the control group, the success rate of weaning was higher than the control group, the difference was statistically significant (P <0.05). Conclusion Both invasive and non-invasive sequential mechanical ventilation have significantly improved clinical outcomes in the treatment of severe pneumonia with respiratory failure.