论文部分内容阅读
探讨婴幼儿肺炎及并发心力衰竭时血清心肌酶的变化。方法采用病例对照方式，对４１例婴幼儿肺炎并发心衰和２０例无合并症的婴幼儿肺炎患者及２０例健康婴幼儿血清心肌酶进行检测；同时分析了血清心肌酶与呼吸频率、心率的关系。结果心衰组血清心肌酶ＬＤＨ、ＡＳＴ、ＣＰＫ、α－ＨＢＤ较健康组高（Ｐ＜０．０５），ＬＤＨ、ＡＳＴ、ＣＰＫ较肺炎组高（Ｐ＜０．０５）；肺炎组血清ＬＤＨ、ＡＳＴ、α－ＨＤＢ较健康组高（Ｐ＜０．０５）；心衰组心衰恢复期ＬＤＨ、ＡＳＴ、α－ＨＢＤ仍较健康组高（Ｐ＜０．０５）。结论婴幼儿肺炎血清心肌酶ＬＤＨ、ＡＳＴ、α－ＨＢＤ可增高；血清心肌酶在肺炎过程中如果明显增高，ＬＤＨ、ＡＳＴ、ＣＰＫ分别接近２５０、５２、１７７时，可能出现心衰或ＭＯＦ
To investigate the changes of serum myocardial enzymes in infantile pneumonia and concurrent heart failure. Methods 41 cases of infantile pneumonia complicated with heart failure, 20 cases of infantile pneumonia without complications and 20 cases of healthy infants were detected by case control method. Serum myocardial enzymes, respiratory rate, heart rate relationship. Results Serum LDH, AST, CPK and α-HBD in patients with heart failure were significantly higher than those in healthy controls (P <0.05), LDH, AST and CPK were higher in patients with pneumonia than those in patients with pneumonia (P <0.05) AST, α-HDB were higher than those in healthy group (P <0.05). LDH, AST and α-HBD in CHF group were still higher than those in healthy group during heart failure recovery (P <0.05). Conclusions Serum myocardial enzymes LDH, AST and α-HBD may be increased in infants with pneumonia. Serum myocardial enzymes may be associated with heart failure or MOF when LDH, AST and CPK are close to 250, 52 and 177, respectively.