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目的 探讨糖耐量低减(IGT)患者尿白蛋白排泄率(UAE)与不同血压指标的关系。方法 对44例IGT患者均进行动态血压(ABPM)监测,心血管自主神经功能测试,UAE测定。结果 与UAE正常组比较,UAE增高组ABPM多项指标增高,夜间血压降低幅度减少,24小时血压曲线平坦。UAE与夜间舒张压(DBP)、收缩压(SBP)负荷、DBP负荷、24hDBP以及24hSBP呈显著正相关,与昼夜血压差值呈显著负相关。结论 UAE增高的IGT患者已经开始出现血压的异常改变。
Objective To investigate the relationship between urinary albumin excretion rate (UAE) and different blood pressure indexes in patients with impaired glucose tolerance (IGT). Methods 44 cases of IGT patients were monitored by ABPM, cardiovascular autonomic nerve function test and UAE. Results Compared with the normal UAE group, the number of ABPM increased in UAE increased group, decreased in nighttime blood pressure decreased, and the blood pressure curve in 24 hours was flat. There was a significant positive correlation between UAE and diastolic blood pressure (DBP), SBP load, DBP load, 24hDBP and 24hSBP. There was a significant negative correlation between UAE and diurnal BP. Conclusions Abnormal changes in blood pressure have begun to occur in patients with elevated UAE.